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Infertility is a common health condition that has been plaguing about 7% to 15% of all the couples, and it affects both males and females. It is defined as inability to conceive after a year of sexual intercourse without contraception.
Major Causes of Infertility
Infertility can have a variety of causes, which results in a variety of classifications based on how these causes are approached. A core reason is extremely difficult to identify since, like other multifactorial disorders, it is influenced by environmental factors in addition to genetic and other epigenetic abnormalities or variations.
In the end around 30% to 50% infertility cases are genetic in nature which makes infertility really difficult to treat as clinical research is only still catching up with the requirements of basic research needed. With the completion of the human genome project and advancements in medical technology, the identification of new disorders has increased through the introduction of 10 to 15 new genetic tests every year.
Genetic Causes and Infertility
One of the major genetic causes of infertility among couples is chromosomal alterations in either numerical or structural manner. Along with these chromosomal alternations, genetic disorders are also exhibited at the DNA level. In such cases, specific genetic tests are needed to determine the exact cause.
Genetic Causes of Infertility in Men
The major genetic causes of infertility in men are:
- Klinefelter’s syndrome
- Microdeletions on the Y chromosome
- Sperm DNA fragmentation
- Frequent mutations: CFTR and AR genes
- Other mutations affecting fertility in men
Genetic Causes of Infertility in Women
The major genetic causes of infertility in women are:
- Turner syndrome
- Mutations in the FMR1 gene
- Triple X syndrome
- Mutations in the FSH receptor
- Thrombophilias
Future of Reproductive Medicine
The lack of fertility is a common condition that has been plaguing humans since ancient times and still continues to be a common condition that needs professional attention. With the advent in technology, more and more disorders are being identified, and appropriate solutions are being formulated.
In such a landscape, the need for reproductive medicine specialists is at an all-time high. That’s where StudyMEDIC comes into the picture, with a panel of expert mentors and extensive resources that guarantee world-class hands-on training. We stand at the forefront of reproductive medicine course providers.
Feel free to contact us for more information.
Authored By: Sanad Beevi
By : Admin
